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The SOUL trial achieved its primary objective by demonstrating a statistically significant and superior reduction in MACE of 14% with oral semaglutide compared to placebo
10.1016/j.chest.2019.10.009 Chest
Some studies have shown that GLP-1RAs act on the hypothalamus to promote satiety and reduce food intake, inhibit gastric emptying [52], thereby leading to weight loss and potentially improving upper airway collapsibility
Semaglutide promotes the proliferation and osteogenic differentiation of bone-derived mesenchymal stem cells through activation of the Wnt/LRP5/beta-catenin signaling pathway
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