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doi: 10.3390/antiox11112270 110 SahooDKRoyAChainyGB

Chemogenetic activation of Gipr -expressing neurones in either the hypothalamus or hindbrain decreases food intake in mice, suggesting more than one centrally located population of GIPR neurons regulate appetite 7,8

Women often notice: Increased abdominal fat, even without changes in diet Slower metabolism and reduced calorie burning Increased insulin resistance Loss of muscle mass Persistent hunger and cravings Difficulty sleeping, which further affects weight regulation These changes are rooted in biology, not willpower

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