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Mood changes: Some individuals experience irritability, anxiety, or emotional ups and downs, particularly as the medication wears off

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Furthermore, treatment with Pluronic L-81, a surfactant that inhibits chylomicron formation, significantly attenuates the anorectic effects of intraduodenal lipids and attenuates both CCK release and celiac and cervical vagal afferent activation following lipid infusion 40,109,156,186