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The researchers also wanted to understand if the GLP-1 system itself plays a role in how these cancers behave

Heres how different groups responded to treatment: Race and Ethnicity : Clinical benefits were consistent across all racial and ethnic groups Type 2 Diabetes : Patients without diabetes achieved higher total body weight loss (16.9%) versus those with diabetes (9.9%) at 12 months Body Mass Index (BMI) : After two years of treatment, 52.4% of participants moved down at least one BMI category Results show that 12% of adults receiving semaglutide reached a healthy BMI of 25 kg/m or less, compared to only 1.2% in the placebo group

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By contrast, patients with PBH had a 5-fold increase in meal-stimulated serotonin