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Multiple independent research groups have replicated findings across different contexts

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This is one reason theyve attracted interest from researchers studying wound healing, skin regeneration, and hair biology

Patients should: Follow the dose escalation schedule to minimise side effects Attend regular follow-up appointments to monitor progress and safety Engage with dietetic support to ensure adequate nutrition whilst reducing calorie intake Combine medication with increased physical activity (aim for 150 minutes moderate-intensity exercise weekly, plus muscle-strengthening activities on at least 2 days per week, as per UK Chief Medical Officers' guidelines) Structured lifestyle programmes : NICE recommends multicomponent interventions including dietary modification, physical activity, and behavioural strategies