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Oily and acne-prone skin has different needs

There is also a theoretical risk of increased incidence of skin cancer with loss of melanin in previously protected individuals

Wang A, Tang H, Zhang N, et al

In TRIUMPH-4, nausea reached up to 43% at the 12mg dose, and retatrutide introduced a dysesthesia (altered skin sensation) signal not seen with semaglutide or tirzepatide

A broader review found it might brighten skin in sun-exposed areas but labeled the overall evidence as "inconclusive" due to mixed study quality (PubMed Systematic Review)

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