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Tardive dyskinesia (more common with metoclopramide than domperidone) and QTc (corrected QT interval) prolongation with the potential for arrhythmia are important concerns, although the risk of tardive dyskinesia may be as low as 0.1% per 1000 patient-years with metoclopramide [71]
Los Farmacuticos de Atencin Primaria contarn con los mdicos prescriptores para que consideren la interrumpcin del tratamiento mientras persistan los problemas de suministro
GIP receptor activation at low doses supports mitochondrial function in adipose tissue and may contribute to improved fatty acid metabolism independent of the dramatic appetite suppression seen at full doses
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According to the SmPC, the most commonly reported side effects include: Nausea (reported in 12-24% of patients, particularly during dose escalation) Diarrhoea (affecting approximately 13-22% of users) Vomiting (occurring in 6-10% of patients) Abdominal pain and discomfort Constipation (reported in 5-17% of patients) These side effects are generally more common during dose escalation and may decrease over time
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