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With Semaglutide, we're noticing our patients not just lose weight, but also gain a clearer complexion and overall improved health
In the context of MASLD/MASH, analogous rebound phenomena would be expected: regression of achieved steatosis resolution and potential re-emergence of inflammatory activity and fibrogenic stimuli upon drug withdrawal
The psychosocial burden of obesity
However, without ongoing interventionwhether pharmacological or behaviouralmost patients will gradually return towards their pre-treatment metabolic state
Unlike topiramate, GLP-1 therapy poses no cognitive risk and is not contraindicated in pregnancy
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