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The mechanistic plausibility is strong (NNMT inhibition increases NAD+ without the gastrointestinal side effects of high-dose nicotinamide), and the short-term tolerability profile is excellent, but we mean this sincerely: if you're using this compound for durations beyond what the published trials covered, you are operating in uncharted territory
Special populations, such as post-bariatric surgery patients and those on metformin, may require tailored dosing regimens to ensure adequate vitamin B12 levels
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There are currently no randomized, controlled clinical trials examining the effects of BPC-157 in humans
Combining they enhance tendon, ligament, muscle, gut, and nerve repair
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