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GLP-1 medications typically achieve this threshold within 8 to 12 weeks, though individual timelines vary
This enhancement of neurotrophic signalling leads to rapid improvements in mood and cognitive flexibility, aligning with the neuroplasticity-based hypothesis of MDD, which posits that MDD arises from widespread deficits in neuronal plasticity and connectivity [229]
=========================================================================== Source: Tucker, Miriam, E
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NICE guidance recommends regular monitoring of patients on GLP-1 receptor agonists, including assessment of gastrointestinal tolerability, weight changes, and glycaemic control
