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Notably, microbial imprinting in the respiratory epithelium may dynamically regulate future immune responses by modulating cytokine output such as IL-1b and IL-8 (149), resembling the trained immunity seen in macrophages

Cancer Chemother Pharmacol

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Gene expression on BDNF and SK-3 was quantified using real-time PCR, revealing that VPA reduced the expression BDNF, which plays a crucial role in synaptic plasticity and neuronal survival, and increased GSK-3, which is involved in neurodevelopment and neuroinflammation whereas crocin dose-dependently normalized both markers (Hosseini et al., 2025)

For instance, BPC-157 is touted for healing many types of injuries from [those of the] tendons and muscles to the gut and brain, says Kumar