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Physiologically based pharmacokinetic modeling for chlorinated paraffins in rats and humans: Importance of biliary excretion

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Therapeutic-Model Protocol Dose: 0.50 1.00 mg (= 2040 clicks) Duration: 6 8 weeks Frequency: Daily Cycle Interval: 2 3 weeks off between cycles Goal / Description: Higher dose to assess enhanced lipolysis and energy utilization

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