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Start at 1,000 mg per day before a workout and assess tolerance before increasing

Critically, pharmacological profiling using both GHRP receptor antagonists and GHRH antagonists confirmed that ipamorelin stimulates GH release exclusively via the GHRP/ghrelin receptor pathway the same receptor used by GHRP-2 and GHRP-6 rather than through the GHRH receptor

doi: 10.1186/s12974-019-1638-6 69

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I'm using mine to good effect and intend to use up the whole box - I've got another couple of month's worth of similar dated ampoules