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Finally, this study had a fairly short follow-up time, so it does not necessarily show how GLP-1RAs affect long-term depression risk
It is actually straightforward once you understand the steps
Semaglutide is a synthetic 31-amino-acid analogue of human GLP-1, studied in preclinical models as a selective agonist of the GLP-1 receptor
Orlistat (Xenical): This drug doesnt appear to cause constipation, but it does cause other GI side effects like oily stools and urgency with bowel movements
These findings are worth noting they are part of why researchers remain interested in the compound
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