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Our earlier study on GK rats subjected to moderate exercise training has shown improvement in cardiac muscle contractile dysfunction and relaxation in myocytes, which are relevant to improvement in diabetes-induced myocardial dysfunction (Salem et al., 2013) Our studies have also demonstrated alterations in redox metabolism, oxidative stress, and mitochondrial dysfunction in the tissues of ZDF type 2 diabetic rats, another animal model of type 2 diabetes (Raza et al., 2004

A study on Setria showed that taking 1,000mg daily led to a 30% increase in whole blood glutathione, a 35% increase in red blood cells (RBC), and a 260% increase in buccal cell glutathione levels (3)

This being said, one potential remedy might involve use of antioxidants, which are mostly taken as supplements, together with radiation therapy and/or chemotherapy that causes cellular oxidative damage (11, 12)

[PubMed] [CellPress] Rossignol DA, Frye RE

The first four weeks on weight-loss medication are spent on a starting dose