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These factors could become self-perpetuating as more oxidative stress is generated by the inflammatory responses, promoting persistence of disease

(Source 8) However, it's hard to say this benefit is due to the caffeine when coffee is very high in polyphenol antioxidant compounds, which are beneficial

Together, excessive and reduced production of neuro-toxic and -protective kynurenines, respectively, may exacerbate excitotoxicity and neuroinflammation, establishing a feed-forward cycle of KP dysregulation, 5-HT depletion, HPA axis hyperactivity, and increased vulnerability to MDD

Copper peptides at 4% stimulate significant cellular activity

G., Sarti, P., Leandro, P