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Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans, Stier H., Vos E., Kenley D., Journal (Journal of Endocrinology and Metabolism, Volume 3, Issues 12, 2013, Pages 715)

The 2006 Ionescu paper documented that pulsatile GH secretion persists even under continuous receptor stimulation, suggesting somatotroph-intrinsic pulsatile release dynamics independent of receptor-binding temporal patterns (PMID 17018654)

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