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Symptoms matching TMAU can also occur when there is no genetic cause, yet excessive TMA is excreted - this has been described as secondary trimethylaminuria (TMAU2)

PMID: 40017118 J Lipid Res Microglial activation and hypothalamic structural plasticity in HFD obesity: insights from semaglutide and minocycline

These findings suggest that GLP-1, GIP and GCGR tri-agonists have the therapeutic potential to alleviate diabetic post-diagnosis complications and provide more efficacious treatments for patients

More serious adverse events observed though at low frequencies included gallbladder-related disorders (such as cholelithiasis), which are a recognised class effect of GLP-1 receptor agonists