This shows that while retatrutide is more impressive, it is not fair to say that it is better than tirzepatide
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[1] [2] The pharmacokinetic properties of each medication determine its recommended dosing frequencysemaglutide and tirzepatide are typically administered once weekly due to their longer half-lives (approximately one week for semaglutide), whilst liraglutide has a shorter half-life (approximately 13 hours) and requires daily injections
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described a case of 66-year-old women with bipolar disorder, who suffered severe reversible cognitive impairment because of VPA toxicity