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They have received extensive attention for their antioxidant, anti-inflammatory, anti-mutagenic and anti-cancer properties, as well as their ability to protect against cardiovascular disease [122]
10.1161/CIRCRESAHA.119.316007 64
IDH mutation impairs histone demethylation and results in a block to cell differentiation
Whether this decline is a cause or consequence of aging and disease remains an active area of research
After 96 h culture, cells were harvested and the viability was determined by a MTT (methylthiazolyldiphenyl-tetrazolium bromide) colorimetric procedure 55 and apoptosis by a flow cytometric method 56
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