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Furthermore, building upon the existing Modified Multiple Platform Method (MMPM) animal model, our research seeks to develop a dual-factor model that integrates sleep and dietary factors (by integrating HFD, ADF, and MMPM) to more accurately reflect clinical pathogenesis, and to investigate whether this model results in disruptions to energy metabolism and oxidative stress-induced brain damage in model rats

MTMR7 overexpression suppresses mTORC1 activation by phosphorylating p62 and dissociating the mTORC1 component Raptor, resulting in decreased HK activity and subsequent VSMC phenotypic remodeling and vascular repair [66]

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WADA status BPC-157 BPC-157 has no approval from any governmental regulatory health authority for human therapeutic use, and as such falls under WADA category S0 (Non-Approved Substances), prohibited at all times (ref

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