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These are often most noticeable when starting or increasing the dose and usually improve over time
A brief temperature equilibration of 5 to 10 minutes is sufficient if cold injections bother you
They might notice an increase in weight around the stomach area
SLC22A12 gene encoding for the urate transporter hURAT1 defects leads to primary renal hypouricemia characterized by increased UA excretion from a reduced reabsorption (Tana et al., 2018)
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