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Journal of Anti-Aging Medicine, 4(2), 133-144
How PlexusDx Supports a More Personalized Approach PlexusDx's Precision Peptide Genetic Test examines key variants in the GLP-1 receptor (rs6923761), GIPR receptor (rs1800437), FTO (rs9939609), and MC4R (rs17782313) pathways
Set point resistance : Your body defends against further weight loss through hormonal shifts, including changes in leptin, ghrelin, and insulin sensitivity, that increase hunger and slow metabolism
Should be taken with the first bite of breakfast, lunch, and dinner the hypoglycemic goal in diabetics typically cannot be met with these drugs alone Side Effects: bloating, gas, abdominal discomfort, diarrhea these side effects develop due to the fermenting of undigested carbohydrate in the colon to fatty acids, with resultant release of gas side effects can diminish over time due to upregulation of -glucosidase in the distal small intestine, which increases glucose absorption & reduces the amount of carbohydrate entering the colon Major drug interactions: ) MAO inhibitors Notes: -glucosidase inhibitors are infrequently prescribed in the US because of their prominent GI side effects & limited ability to lower glucose levels -glucosidases are a family of enzymes with different carbohydrate specificities, and include sucrase, maltase, glucoamylase & dextranase References: Masharani U, Kroon L (2024): Pancreatic Hormones & Antidiabetic Drugs (Chapter 41)
The medication was compensating for a genuine biological imbalance
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