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E., Burns, A., Selby, A

10.1111/j.1600-0404.1990.tb00952.x 16

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Collectively, these findings position aza-substitution as a rational and intrinsically efficient strategy to stabilize therapeutic peptides while preserving native functionmarking a shift from empirical modification toward data-driven, atom-level peptide design that could simplify manufacturing and reduce development costs for durable peptide therapeutics