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The question is which works better for specific goals, which is more tolerable, which has better long-term data, and most critically, which you can actually access
For patients in Miami who are exploring options beyond GLP-1 medications, this mechanism is clinically meaningful
In addition to the studies demonstrating the central effects of GLP-1 and its analogs on satiety and reduction of energy intake, there are studies showing other central effects of GLP-1 involving BAT
Gradual progress is typically more manageable and lasting
Current guidelines recommend discontinuing GLP-1RAs one week prior to weekly dosing and on the day of surgery for daily dosing, with gastric volume assessment via ultrasound prioritized
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