The researchers concluded that impaired GH secretion in aging is a functional and potentially reversible state, not a permanent decline
Ipamorelin, while less potent per dose, produces clean GH release without these side effects and maintains efficacy with continuous use
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The native peptide has limited blood-brain barrier penetration, which is part of why some recent research has focused on DSIP fusion peptides combined with cell-penetrating sequences (like Tat) to improve CNS delivery
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