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At this stage, the combined inhibitory effect of the dual signals on this neuronal population is significantly more potent than that achieved by GLP-1R mono-agonists

J Mol Med (Berl)

P.KropacE.DoM

MEDI0832 (now known as cotadutide) is a balanced co-agonist based on the peptide sequence of glucagon, modified at specific amino acid positions in addition to a palmitic fatty acid side chain to prolong activity

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