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Low total vitamin C plasma level is a risk factor for cardiovascular morbidity and mortality in hemodialysis patients

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Here is the key caveat: most of this mechanism is extrapolated from individual ingredients , often studied as oral supplements and sometimes only in animals or specific patient groups

The inclusion of patients on diverse regimens, both preserved and preservative-free, supports the generalizability of the effects of the formulation across a representative spectrum of real-world therapy