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Stacking with other experimental peptides (like AOD-9604) is speculative and not clinically tested

Moreover, preclinical studies of individual peptides have not reported significant acute toxicity

Unlike taking growth hormone directly, they do not shut down endogenous production

In line with the idea that peripheral immune cells are not passive responders but function as key hubs linking systemic inflammation to central neurodegeneration, we propose that peripheral effects should be considered as mechanistic contributors to neuronal death in PD, as clinically accessible targets for biomarker development, and as potential therapeutic strategies to slow and hopefully halt its progression

Cell 117 , 495502 (2004)