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Multiple trials indicated that it outperforms placebo, 379,380 whereas comparisons with acetazolamide have yielded contradictory results
TRIUMPH-1's nested sleep apnea substudy also reported positive data at the ADA Scientific Sessions on June 6, 2026, showing a 60.6% reduction in the apnea-hypopnea index
Since fatty acid oxidation depends on the presence of carnitine, an increase in the level of carnitine may cause an increase in the rate of fatty acid oxidation and thus contribute to the energy supply
However, more research is needed to understand the exact mechanism fully
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