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Key ones include: Magnesium citrate (200-400 mg daily): Helps prevent constipation, supports sleep quality, and reduces muscle cramps B12 or methylcobalamin: GLP-1 agonists can reduce B12 absorption over time, and some compounded formulations include B12 in the compound for this reason Electrolytes: Sodium, potassium, and magnesium supplementation helps offset the dehydration risk from reduced food intake Protein powder: A practical way to maintain protein targets when appetite makes eating full meals difficult Some compounded formulations include additional ingredients like glycine , niacinamide , or glycine plus B12 combinations

Neurobiology of hypoxic-ischemic injury in the developing brain

GLP-1 agonists affect diverse obesity etiopathogenic processes such as abnormal food intake regulation, adipocyte dysfunction, insulin resistance, adipokine production, inflammation, endothelial dysfunction, lipid metabolism, and oxidative stress

Both tirzepatide and semaglutide (the active ingredient in Ozempic and Wegovy) have been associated with fatigue in clinical trials

Eating smaller, more frequent meals (5-6 times daily) prevents the stomach from becoming too full or too empty, both of which can trigger nausea