Glutathione is critical for metastasis, and we determined that the rate-limiting enzyme of glutathione synthesis, GCLC, becomes overexpressed in patient liver metastases, promotes cell survival under hypoxic and cell-dense conditions, and mediates metastatic liver colonization
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Adipocyte Phenotypes : Investigating the reduction of lipogenesis (fat accumulation) without killing the cell
Cell 144 PompellaA.VisvikisA.PaolicchiA.De TataV.CasiniA
Glucagon-like peptide-1 (GLP-1) receptor agonists, a new class of drugs sold under names such as Ozempic, Wegovy, and Zepbound, are soaring in popularity for their ability to achieve and sustain substantial weight loss and improve cardiometabolic health