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The recommended dosage of phentermine and topiramate extended-release capsules in patients with mild renal impairment (CrCl greater or equal to 50 and less than 80 mL/min) is the same as the recommended dosage for patients with normal renal function

Free Radic Biol Med , 36:5364

Although MDD supports their usage, the field of etiology research is still evolving by substituting peripheral epigenetic changes for brain activity

Common experiences may include: Nausea Decreased appetite Mild gastrointestinal discomfort Injection site tenderness These side effects are typically temporary and may subside as the body adjusts to the medication

PLoS ONE 7:e49121