Rossi, R., Giustarini, D., Milzani, A
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doi: 10.1007/s001250050604 12 HedmanCAFrystykJLindstromTOskarssonPArnqvistHJ
The study reported that participants "regained two-thirds of their prior weight loss." A meaningful share of the loss is muscle: across body-composition studies, roughly a quarter of the weight lost is lean mass (muscle), with the rest fat (Karakasis and colleagues, network meta-analysis, Metabolism , 2024), and the honest range landing between about 15% and 40% (Hierholzer and colleagues, review, 2026)
PMID: 41844462 Ahmed F et al