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Am J Clin Nutr 76 : 646652 Lyons J, Rauh-Pfeiffer A, Ming-Yu Y, Lu XM, Zurakowski D, Curley M, Collier S, Duggan C, Nurko S, Thompson J, Ajami A, Borgonha S, Young VR, Castillo L 2001 Cysteine metabolism and whole blood glutathione synthesis in septic pediatric patients

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A trial targeting BCAA catabolism should enroll patients with evidence of BCAA pathway dysfunction, not all patients with hypertrophy

For type 2 diabetes, the typical starting dose is 500 mg once or twice daily with meals, gradually increased based on glycemic response and tolerance