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doi:10.1016/j.coph.2013.09.006 131

They used these to model the trajectory of weight regain, including to extrapolate beyond 52 weeks

Some patients may require levothyroxine dose reductions as they lose weight, while the relationship is not always linear or predictable

And we learned through that process working on this committee that you were the one to be the champion of pushing this towards obesity, and it would've easily been missed because as we've been discussing, the weight loss in people with diabetes was small, but you push for it

BMI thresholds still exist because clinical trials primarily studied patients meeting specific BMI requirements, and FDA indications and insurance policies are generally based on those populations