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It was noted that lapatinib at the dose of 100 mg/kg exhibited more evident protection against seizure phenotype than that by the dose of 50 and 100 mg/kg lapatinib had no significant effect on weight gain, indicating a good tolerance of lapatinib (Figure 1F)
The heart benefit and the weight loss benefit appear to operate on different timescales and through different mechanisms
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Treating Mitochondrial Dysfunction: A Layered Strategy Treatment depends on whether the problem is a primary mitochondrial disease, acquired dysfunction or one component of a broader psychiatric, neurological or metabolic illness
Inhibition of inflammatory microglia by dietary fiber and short-chain fatty acids
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