Bassi N, Karagodin I, Wang S, et al
The strongest predictors are baseline IGF-1 level, age, sleep quality (7-9 hours nightly), training consistency (4-6 days/week), diet quality, and protocol adherence
The molecule simply does not survive the journey
GLP-1s like semaglutide and tirzepatide have proven wildly successful at helping treat type 2 diabetes, manage weight, and deliver a ton of other health benefits, such as improving heart health and reducing addictive behaviors like drinking
GWAS of GLP1 medication efficacy We performed a GWAS of the percentage BMI loss phenotype ( n = 15,237), and identified a strong genome-wide significant association on chromosome (chr.) 6 (Fig