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The market remained relatively static until 2021 when Novo Nordisks semaglutide (Ozempic for diabetes and Wegovy for obesity) was approved, showing nearly 10% weight loss over two years

Clinical studies show that 1525 % of people using GLP-1 or dual-agonist medications experience mild diarrhoea at some point typically during the first month or while the dose is being increased

Int J Exerc Sci 11(2):404 Chee C, Shannon CE, Burns A, Selby AL, Wilkinson D, Smith K, Greenhaff PL, Stephens FB (2021) Increasing skeletal muscle carnitine content in older individuals increases whole-body fat oxidation during moderate-intensity exercise

The inclusion of soothing agents like aloe vera and turmeric extract ensures that the skin remains calm and comfortable during use

5b, Supplementary Fig