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For Studies 2, 3 and 4, the primary efficacy parameters were mean percent change in body weight and the percentages of patients achieving greater than or equal to 5% weight loss from baseline to Week 68

Men are generally at higher risk than pre-menopausal women, though this difference diminishes after menopause

doi:10.1038/s42255-020-00327-x [2] Zhao X, Wang M, Wen Z, Lu Z, Cui L, Fu C, Xue H, Liu Y, Zhang Y

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Switching Medications : Its important to consult with a professional while considering switching between Semaglutide or Tirzepatide