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For others, they can trigger painful episodes known as gallbladder attacks

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The primary risks include bile duct stones or obstruction, compounded gastrointestinal side effects (nausea, diarrhoea), and pancreatitis

Larger prospective trials, stratified by hormone formulation, route of delivery, timing of initiation, and baseline metabolic health, will be required to establish causality, characterize which women benefit most, and track outcomes across the full range of health domains this article has examined