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Ephelides (plural of ephelis) are usually found in fair-skinned individuals, are due to sunlight exposure, occur in childhood, tend to diminish with age, and are lighter in appearance

For other confirmed or suspected malabsorption, vitamin B12 replacement should be offered and intramuscular treatment should be considered instead of oral treatment

The potential for drug interactions increases with polypharmacy, particularly with medications that affect gastric emptying or require specific timing relative to meals

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A rapid escalation is associated with low blood sugar levels and severe GI side effects such as severe abdominal pain, nausea, vomiting, and inflammation of the pancreas (pancreatitis)