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Despite minor fluctuations, the number of AE reports for DPP-4 inhibitors has remained low in recent years
These include severe or persistent abdominal pain, vomiting that will not stop or that prevents you from keeping fluids down, signs of dehydration, blood in the stool, or symptoms that suddenly get worse instead of slowly improving
The broader guide on tirzepatide and autoimmune disease provides additional context
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Because these drugs essentially act as hormones (which, once metabolized, lose their efficacy), this drop in adherence may not bode well for maintaining the effects of these drugs in the long term
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