Gradual titration is the standard of care because it significantly reduces the frequency and severity of gastrointestinal side effects, such as nausea and vomiting
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But the patients that have repair of their pelvic venous disease often tell me that initially there's back pain, initially there's a little bit of recuperation, but then some of them are like, wow, immediately like day one, I got out of the procedure and I felt like color had come back to my face
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