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The temporal pattern is important: symptoms typically peak within the first 4-8 weeks of therapy or after dose escalation, then often improve as physiological adaptation occurs
Safety profile: Oral semaglutide has a safety profile consistent with injectable forms, offering confidence in its long-term use
therefore, diligent postmarketing surveillance to elucidate the risk of medullary thyroid carcinoma (MTC) is ongoing
Efficacy and safety of tirzepatide, GLP -1 receptor agonists, and other weight loss drugs in overweight and obesity: a network meta-analysis
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