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In fact its a time bomb and there will be guaranteed casualties amongst B12 deficient patients who only take oral tablets during this period
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This activation involves phosphorylation and nuclear accumulation of TAp63 in oocytes, which subsequently triggers the expression of pro-apoptotic Bcl-2 family members, including PUMA, NOXA, and Bax, initiating the apoptotic pathway (Suh et al., 2006
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