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Clinical outcomes have illustrated that semaglutide may offer superior efficacy, wich is particularly evident in its ability to significantly reduce HbA1c levels and support sustainable weight loss

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Adams JB, Baral M, Geis E, Mitchell J, Ingram J, Hensley A, et al

But an increase in hunger can still come as a bit of shock especially if you've been taking semaglutide for some time

TRAILBLAZER-ALZ 4 (NCT05108922) is a phase 3, open-label, head-to-head comparison of amyloid clearance by either donanemab or aducanumab that began in November 2021 after the US FDA approval of aducanumab