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Eur J Appl Physiol Occup Physiol

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An animal study in a reserpine-induced fibromyalgia model demonstrated that TRPA1 activation in glial cells promotes oxidative stress via NADPH oxidase (NOX1), leading to neuroinflammation and nociceptor sensitization (9)

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Although the number of injections that would be administered would very much depend on the extent of the nerve damage, they are normally administered over several weeks or months