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Research shows it enhances fibroblast migration to injury sites through the FAK-paxillin pathway, improves collagen fiber organization and cross-linking, promotes angiogenesis to improve nutrient delivery, and reduces inflammatory mediators while preserving beneficial healing signals

Certain probiotic strains direct mucosal immune activity by inducing the secretion of key cytokines and B-cell growthpromoting factors, including interleukin-4 (IL-4), interleukin-5 (IL-5), and interleukin-13 (IL-13) (215, 244)

While the preclinical safety profile appears favorable (few adverse effects reported in animal studies), this does not guarantee the same in humans, especially with prolonged use

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