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Who might it be best for Given the mechanism, benefits and limitations, the ideal candidate profile might look like this: Individuals who have stubborn fat (especially visceral/subcutaneous) despite diet/exercise efforts, and want to improve body composition without major muscle loss
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The study authors did a commendable job bolstering the case that this was a good apples to apples comparison by first comparing only people getting new diabetes medication, then statistically controlling for a whole range of other sociodemographic factors (age, education, race/ethnicity, area-level income) and MANY baseline health characteristics and health behaviors
Early signals are already emerging: on the morning of Foundayo's approval, Calibrate clinicians immediately noted calls from members on injectable GLP-1s asking about transitioning to orals
He had a handful of patients on CPAP who were prescribed these medications for diabetes or obesity by their primary care physicians and were able to stop using CPAP
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